| Primary Identifier | MGI:1914449 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 67199 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable amyloid-beta binding activity; protein folding chaperone; and unfolded protein binding activity. Acts upstream of or within B cell activation; actin cytoskeleton organization; and brain development. Predicted to be part of prefoldin complex. Predicted to be active in cytoplasm. Is expressed in limb and limb mesenchyme. Orthologous to human PFDN1 (prefoldin subunit 1). PHENOTYPE: Mice homozygous for a gene trapped allele display reduced birth size, slow weight gain, loss of neuron tracts in the brain, uncoordinated movement, impaired B and T cell development and function, mucus clearance defects, hydrocephaly, and premature deathpreceded by physical wasting. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
