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Publication : Molecular cloning, structure and expression analysis of a full-length mouse brain glutamate dehydrogenase cDNA.

First Author  Tzimagiorgis G Year  1991
Journal  Biochim Biophys Acta Volume  1089
Issue  2 Pages  250-3
PubMed ID  1711373 Mgi Jnum  J:11265
Mgi Id  MGI:59704 Doi  10.1016/0167-4781(91)90017-g
Citation  Tzimagiorgis G, et al. (1991) Molecular cloning, structure and expression analysis of a full-length mouse brain glutamate dehydrogenase cDNA. Biochim Biophys Acta 1089(2):250-3
abstractText  We isolated and analysed a full-length mouse brain glutamate dehydrogenase (GLUD) cDNA as a preliminary step to use the mouse model for the investigation of GLUD function in neurotransmission and neurodegeneration. GLUD coding sequences were found highly conserved among mouse, human and rat. Northern blots revealed two transcripts with different ratios in different mouse organs implying some mechanism of tissue-specific expression. In contrast to human, mouse GLUD gene family appears not to contain an intronless member.
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