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Protein Coding Gene : Mybl2 myeloblastosis oncogene-like 2

Primary Identifier  MGI:101785 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  17865
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within cellular response to leukemia inhibitory factor and mitotic spindle assembly. Located in nucleus. Part of Myb complex. Is expressed in several structures, including brain; early conceptus; genitourinary system; hemolymphoid system; and skin. Used to study acute myeloid leukemia and myelodysplastic syndrome. Orthologous to human MYBL2 (MYB proto-oncogene like 2).
PHENOTYPE: Mice homozygous for disruptions in this gene die as embryos shortly after implantation. [provided by MGI curators]
  • synonyms:
  • Mybl2,
  • Bmyb,
  • B-Myb,
  • myeloblastosis oncogene-like 2,
  • MGD-MRK-18593

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