| Primary Identifier | MGI:2181411 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 246787 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable D-glucose transmembrane transporter activity; alpha-glucoside transmembrane transporter activity; and glucose:sodium symporter activity. Involved in renal glucose absorption. Located in apical plasma membrane. Is expressed in urinary system. Human ortholog(s) of this gene implicated in renal glycosuria. Orthologous to human SLC5A2 (solute carrier family 5 member 2). PHENOTYPE: Mice homozygous for a null allele exhibit increased urine glucose, increased eating and drinking behaviors, increased circulating renin activity, decreased urine osmolality, decreased serum aldosterone levels, polyuria, and decreased glucose renal reabsorption. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
