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Protein Domain : Tetratricopeptide repeat protein 26

Primary Identifier  IPR030511 Type  Family
Short Name  TTC26
description  This entry refers to Tetratricopeptide repeat protein 26 (TTC26, also known as Intraflagellar transport protein 56).TTC26 is required for ciliogenesis and normal cilia function in zebrafish []. A mutation in the mouse TTC26 gene leads to impaired hedgehog signalling and causes hop-sterile (hop), which is characterised by a hopping gait, polydactyly, hydrocephalus, and male sterility []. Mouse TTC26 binds directly to the Ift46 subunit of Intraflagellar Transport (IFT) complex B, however, the TTC26 defect does not result in a decrease in the number or length of primary cilia [].

0 Child Features

0 Parent Features

6 Protein Domain Regions