| Primary Identifier | MGI:4936855 | Allele Type | Transgenic |
| Attribute String | Constitutively active, Inserted expressed sequence | Gene | Tg(IVL-MAP2K1*S217E*S221E)3376AFmw |
| Strain of Origin | (CBA x C57BL/6)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A constitutively activated map 2 kinase kinase 1 having two point mutations causing Serine to glutamic acid residue changes at positions 217 and 221 was placed under the control of the involucrin promoter. Three founder lines are reported. Line 3376A has a high relative insert copy number. |
