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Protein Coding Gene : Ppme1 protein phosphatase methylesterase 1
Primary Identifier  MGI:1919840 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  72590
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables lncRNA binding activity. Is expressed in several structures, including alimentary system; clavicle; ganglia; lower urinary tract; and nasal cavity epithelium. Orthologous to human PPME1 (protein phosphatase methylesterase 1).
PHENOTYPE: Targeted disruption of this gene causes virtual loss of the demethylated form of phosphoprotein phosphatase 2A in the nervous system and peripheral tissues. Homozygous null mice fail to initiate normal breathing or suckling behavior and die within the first day of life. [provided by MGI curators]
  • synonyms:
  • PME-1,
  • 1110069N17Rik,
  • RIKEN cDNA 1110069N17 gene,
  • MGI:1916144,
  • Ppme1,
  • protein phosphatase methylesterase 1,
  • 2700017M01Rik,
  • RIKEN cDNA 2700017M01 gene
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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