Primary Identifier | MGI:5433040 | Allele Type | Targeted |
Attribute String | Modified regulatory region, Null/knockout | Gene | Rr19 |
Transmission | Germline | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The conserved non-exonic enhancer element (E4) upstream of Fezf2 was replaced with a loxP site flanked neomycin resistance gene cassette that was removed by subsequent cre-mediated recombination. qRT-PCR confirmed a severe reduction in Fezf2 transcript expression. |