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Protein Coding Gene : Msrb1 methionine sulfoxide reductase B1

Primary Identifier  MGI:1351642 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  27361
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables actin binding activity; peptide-methionine (R)-S-oxide reductase activity; and zinc ion binding activity. Involved in actin filament polymerization and innate immune response. Acts upstream of or within protein repair. Located in cytoplasm and nucleus. Colocalizes with actin cytoskeleton. Is expressed in extraembryonic component; genitourinary system; heart; inner ear; and skeletal muscle. Orthologous to human MSRB1 (methionine sulfoxide reductase B1).
PHENOTYPE: Mice homozygous for a gene trap allele exhibit oxidative stress. [provided by MGI curators]
  • synonyms:
  • Msrb1,
  • selenoprotein X 1,
  • methionine sulfoxide reductase B1,
  • MGD-MRK-33975,
  • Sepr,
  • DNA segment, Chr 17, Wayne State University 82, expressed,
  • selenoprotein R,
  • SelR,
  • MGI:106283,
  • Sepx1,
  • D17Wsu82e

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For