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Protein Coding Gene : Acer2 alkaline ceramidase 2
Primary Identifier  MGI:1920932 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  230379
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables dihydroceramidase activity. Involved in sphingosine biosynthetic process. Predicted to be located in Golgi apparatus. Predicted to be active in Golgi membrane. Is expressed in several structures, including heart; hemolymphoid system; liver; lung; and stomach. Orthologous to human ACER2 (alkaline ceramidase 2).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit a reduction of sphingoid bases and their phosphates in whole blood, plasma, erythrocytes, and platelets. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2410116I05 gene,
  • Asah3l,
  • N-acylsphingosine amidohydrolase 3-like,
  • Acer2,
  • alkaline ceramidase 2,
  • 2410116I05Rik
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5 Involved In Mutations

Trail: ProteinCodingGene

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Trail: ProteinCodingGene

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