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Protein Domain : DNA ligase 4

Primary Identifier  IPR029710 Type  Family
Short Name  LIG4
description  DNA ligase 4 (LIG4) is involved in DNA double-strand break repair []. In higher eukaryotes it forms a complex with XRCC4, which is responsible for the ligation step during the DNA-PK-dependent non-homologous end joining (D-NHEJ) [, ]. The Ku component of the DNA-PK (DNA-dependent protein kinase) complex contributes to the recruitment of the LIG4-XRCC4 complex at the DNA break site [].

0 Child Features

1 Parent Features

2 Protein Domain Regions