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Publication : Cellular immune response to Listeria in genetically resistant and susceptible mouse strains.

First Author  Rudnicka W Year  1989
Journal  Acta Microbiol Hung Volume  36
Issue  2-3 Pages  341-4
PubMed ID  2631515 Mgi Jnum  J:26389
Mgi Id  MGI:75378 Citation  Rudnicka W, et al. (1989) Cellular immune response to Listeria in genetically resistant and susceptible mouse strains. Acta Microbiol Hung 36(2-3):341-4
abstractText  Relatively Listeria-resistant C57B1/6 mice and more susceptible to the infection DBA/2 mice were immunized with Listeria-antigen (LA). Immunized DBA/2 mice developed weaker delayed hypersensitivity to LA and still eliminated listeriae less effectively than identically immunized C57B1/6 mice. An accessory function of LA-pulsed macrophages of normal C57B1/6 mice was only slightly enhanced as compared with LA-pulsed macrophages of DBA/2 mice. It is suggested that some suppressor lymphocytes, IgM+ and/or FcR+, could be responsible for the enhanced susceptibility of DBA/2 mice to listeriosis.
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