First Author | Rudnicka W | Year | 1989 |
Journal | Acta Microbiol Hung | Volume | 36 |
Issue | 2-3 | Pages | 341-4 |
PubMed ID | 2631515 | Mgi Jnum | J:26389 |
Mgi Id | MGI:75378 | Citation | Rudnicka W, et al. (1989) Cellular immune response to Listeria in genetically resistant and susceptible mouse strains. Acta Microbiol Hung 36(2-3):341-4 |
abstractText | Relatively Listeria-resistant C57B1/6 mice and more susceptible to the infection DBA/2 mice were immunized with Listeria-antigen (LA). Immunized DBA/2 mice developed weaker delayed hypersensitivity to LA and still eliminated listeriae less effectively than identically immunized C57B1/6 mice. An accessory function of LA-pulsed macrophages of normal C57B1/6 mice was only slightly enhanced as compared with LA-pulsed macrophages of DBA/2 mice. It is suggested that some suppressor lymphocytes, IgM+ and/or FcR+, could be responsible for the enhanced susceptibility of DBA/2 mice to listeriosis. |