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Publication : Tctex3, related to Drosophila polycomblike, is expressed in male germ cells and mapped to the mouse t-complex.

First Author  Kawakami S Year  1998
Journal  Mamm Genome Volume  9
Issue  11 Pages  874-80
PubMed ID  9799836 Mgi Jnum  J:50577
Mgi Id  MGI:1306967 Doi  10.1007/s003359900886
Citation  Kawakami S, et al. (1998) Tctex3, related to Drosophila polycomblike, is expressed in male germ cells and mapped to the mouse t-complex. Mamm Genome 9(11):874-80
abstractText  Tctex3 showing restricted expression in male germ cells has been isolated during the process of chromosome walking in the mouse t-complex region. The total sequence of Tctex3 cDNA predicts a protein of 580 amino acids with two C4HC3 type PHD fingers. The region containing this conserved motif is shared among members of the Polycomblike proteins that include the mouse M96 and Drosophila Polycomblike. A partial cDNA for a human homolog of Tctex3, HUTEX3, has also been isolated. Mouse Tctex3 gene was mapped adjacent to Tsc2 gene on mouse Chromosome (Chr) 17, and HUTEX3 was located closely to HSET gene in the HLA class II region of chromosome 6.
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