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Protein Coding Gene : H2ab1 H2A.B variant histone 1

Primary Identifier  MGI:3642445 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  100039319
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable nucleosomal DNA binding activity. Predicted to be involved in heterochromatin formation. Predicted to be part of euchromatin and nucleosome. Predicted to be active in nucleus. Orthologous to human H2AB1 (H2A.B variant histone 1); H2AB2 (H2A.B variant histone 2); and H2AB3 (H2A.B variant histone 3).
PHENOTYPE: Male mice hemizygous for knock-out alleles of H2afb1, H2afb2 and H2afb3 exhibit reduced fertility, teratozoospermia, oligozoospermia and clogged seminiferous tubules. [provided by MGI curators]
  • synonyms:
  • H2A.B variant histone 1,
  • OTTMUSG00000018481,
  • predicted gene, ENSMUSG00000067441,
  • predicted pseudogene 14920,
  • H2A histone family member B2,
  • H2afb1,
  • H2A.Bbd1,
  • Gm14920,
  • ENSMUSG00000067441,
  • predicted gene, OTTMUSG00000018481,
  • H2ab1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

27 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For