| Primary Identifier | MGI:103022 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 19699 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables very-low-density lipoprotein particle receptor binding activity. Involved in several processes, including learning or memory; positive regulation of cell communication; and postsynaptic membrane organization. Acts upstream of or within several processes, including nervous system development; positive regulation of small GTPase mediated signal transduction; and thyroid hormone metabolic process. Located in several cellular components, including dendrite; extracellular matrix; and extracellular space. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Used to study schizophrenia. Human ortholog(s) of this gene implicated in Norman-Roberts syndrome; autistic disorder; and familial temporal lobe epilepsy 7. Orthologous to human RELN (reelin). PHENOTYPE: Homozygotes for most spontaneous or ENU-induced mutations show impaired righting responses, ataxia, tremors, and cerebellum and hippocampus abnormalities. Some mutants show postnatal or premature death and decreased body size while others have abnormal retinas or olfactory bulbs or infertility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
