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Protein Coding Gene : Ggt1 gamma-glutamyltransferase 1

Primary Identifier  MGI:95706 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  14598
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable glutathione hydrolase activity; leukotriene-C(4) hydrolase; and peptidyltransferase activity. Involved in several processes, including cysteine biosynthetic process; glutathione biosynthetic process; and regulation of inflammatory response. Acts upstream of or within spermatogenesis. Located in vesicle. Is expressed in genitourinary system; liver; and yolk sac. Human ortholog(s) of this gene implicated in gamma-glutamyl transpeptidase deficiency. Orthologous to several human genes including GGT1 (gamma-glutamyltransferase 1).
PHENOTYPE: Homozygous mutants may exhibit impaired growth, skeletal abnormalities, cataracts, lethargic behavior, premature greying, sterility, and shortened life span. [provided by MGI curators]
  • synonyms:
  • gamma-glutamyl transpeptidase,
  • MGI:2143665,
  • dwg,
  • CD224,
  • GGT,
  • AI746379,
  • MGI:94942,
  • gamma-glutamyltransferase 1,
  • Ggt1,
  • MGD-MRK-8921,
  • expressed sequence AI746379,
  • dwarf grey,
  • MGD-MRK-10068,
  • Ggtp

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

12 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

2 Driver For