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Protein Coding Gene : Bcl9 B cell CLL/lymphoma 9

Primary Identifier  MGI:1924828 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  77578
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables beta-catenin binding activity. Acts upstream of or within several processes, including myotube differentiation involved in skeletal muscle regeneration; positive regulation of transcription by RNA polymerase II; and skeletal muscle cell differentiation. Located in cis-Golgi network; nucleus; and sarcoplasm. Is expressed in several structures, including brain; eye; head surface ectoderm; metanephros; and thymus primordium. Orthologous to human BCL9 (BCL9 transcription coactivator).
PHENOTYPE: Mice carrying homozygous floxed Bcl9 and Bcl9l alleles, inactivated in muscle cells, exhibit impaired muscle regeneration due to increased apoptosis. [provided by MGI curators]
  • synonyms:
  • MGI:2684976,
  • RIKEN cDNA 8030475K17 gene,
  • MGI:2441728,
  • RIKEN cDNA 2610202E01 gene,
  • MGI:1919744,
  • A330041G23Rik,
  • Gm130,
  • 8030475K17Rik,
  • Bcl9,
  • gene model 130, (NCBI),
  • RIKEN cDNA A330041G23 gene,
  • B cell CLL/lymphoma 9,
  • 2610202E01Rik

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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0 Driver For