Primary Identifier | MGI:2448955 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Lrp5 |
Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 18 was disrupted by a neomycin selection cassette inserted by homologous recombination. Neither normal transcript nor normal protein was detected by Northern and Western blot analyses of liver tissue obtained from homozygous mutant mice. |