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Publication : Organ specific expression of esterase-6 in the house mouse, Mus musculus.

First Author  de Looze SM Year  1982
Journal  Histochemistry Volume  74
Issue  4 Pages  553-61
PubMed ID  7107330 Mgi Jnum  J:6830
Mgi Id  MGI:55302 Doi  10.1007/BF00496669
Citation  de Looze SM, et al. (1982) Organ specific expression of esterase-6 in the house mouse, Mus musculus. Histochemistry 74(4):553-61
abstractText  Esterase-6 in fresh homogenates of heart muscle and testis of the house mouse shows a two band (C allele) or three band (A allele) pattern in disc electrophoresis. These primary bands generated in series of secondary bands upon lowering the pH of the homogenates, and the secondary pattern, possibly resulting from partial proteolysis, was seen in varying degrees in fresh homogenates from a range of organs. Interrelationships between the primary and secondary bands were demonstrated by isoelectric focusing. The esterase-6 content of twenty different organ homogenates was estimated from electrophoretic gels, and a high level of this enzyme was observed in those organs most actively involved in fat metabolism. The possible participation of esterase-6 in fatty acid utilization is discussed. Similarities between esterase-6 of the house mouse and esterase-4 of the rat were demonstrated, further strengthening the view that these enzymes are homologous.
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