| Type | subunit | Description | Homodimer (PubMed:12196028). Heterodimer; efficient DNA binding requires dimerization with another bHLH protein (PubMed:15226298). Forms a heterodimer with TWIST1 and TWIST2 (PubMed:7589808, PubMed:23395635). Forms a heterodimer with NEUROD1; the heterodimer is inhibited in presence of ID2, but not NR0B2, to E-box element (PubMed:23395635, PubMed:18069799). Forms a heterodimer with TCF15; the heterodimer binds E-box element (PubMed:15226298, PubMed:23395635). Forms a heterodimer with MYOG; heterodimerization enhances MYOG DNA-binding and transcriptional activities (PubMed:12196028). Forms a heterodimer with ATOH8; repress transcription of TCF3 and TCF3-NEUROG3 dimer-induced transactivation of E box-dependent promoters (PubMed:23938248). Component of a nuclear TAL-1 complex composed at least of CBFA2T3, LDB1, TAL1 and TCF3 (PubMed:16407974). Interacts with NEUROD2 (PubMed:18214987). Interacts with EP300 (By similarity). Interacts with PTF1A, TGFB1I1 and UBE2I (PubMed:9409784, PubMed:11318877, PubMed:16291758). Interacts with BHLHA9 (By similarity). Interacts with ASB2; the interaction is mediated by SKP2 and targets TCF3 for Notch-induced proteasomal degradation (By similarity). |
