First Author | Uematsu Y | Year | 1988 |
Journal | Immunogenetics | Volume | 27 |
Issue | 2 | Pages | 96-101 |
PubMed ID | 2891614 | Mgi Jnum | J:8974 |
Mgi Id | MGI:57438 | Doi | 10.1007/BF00351082 |
Citation | Uematsu Y, et al. (1988) The same MHC recombinational hot spots are active in crossing-over between wild/wild and wild/inbred mouse chromosomes. Immunogenetics 27(2):96-101 |
abstractText | Four recombinational breakpoints were mapped in the K-A interval of the mouse major histocompatibility complex (MHC) by Southern blot analysis. The breakpoint in B10.SBR, containing a b/s recombinant MHC haplotype, is located about 45 kb upstream of the A beta 2 gene close to the breakpoint in B10.AQR. Crossover in two cas3/cas4 and one cas4/cas3 recombinant haplotypes has taken place in the previously identified K/A beta 3 and A beta 3/A beta 2 recombinational hot spots. The same hot spots are thus active in crossover between two Mus musculus castaneus MHC haplotypes and in crossover between a laboratory and a M. m. castaneus MHC haplotype. |