Primary Identifier | MGI:1858317 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 53600 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable enzyme binding activity and protein transmembrane transporter activity. Predicted to be involved in intracellular protein transport; positive regulation of protein processing; and protein import into mitochondrial matrix. Predicted to act upstream of or within protein transport. Located in migrasome and mitochondrion. Is expressed in several structures, including central nervous system; heart; orbito-sphenoid; submandibular gland primordium; and tooth. Orthologous to several human genes including TIMM23 (translocase of inner mitochondrial membrane 23). PHENOTYPE: Mice homozygous for a gene trapped allele die prior to E3.5. Mice heterogygous for this allele exhibit background sensitive premature aging and increased mortality. [provided by MGI curators] |