| Primary Identifier | MGI:2443160 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 94212 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable SH2 domain binding activity. Involved in negative regulation of T cell activation. Predicted to be located in plasma membrane. Predicted to be active in membrane raft. Is expressed in several structures, including brain and spinal cord. Orthologous to human PAG1 (phosphoprotein membrane anchor with glycosphingolipid microdomains 1). PHENOTYPE: Mice homozygous for a knock-out allele are viable and exhibit no apparent defects in embryogenesis, thymic development, or T-cell functions. Mice homozygous for a different knock-out allele show normal T-cell development albeit with an increased thymocyte population. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
