| Primary Identifier | MGI:107472 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 12745 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables protein folding chaperone. Acts upstream of or within binding activity of sperm to zona pellucida and protein-containing complex assembly. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; brain; gallbladder; genitourinary system; and limb segment. Orthologous to human CLGN (calmegin). PHENOTYPE: Males homozygous for a targeted null mutation exhibit severely impaired fertility associated with an apparent defect in either sperm/zona pellucida binding and/or sperm transit to the oviduct. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
