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Protein Coding Gene : Stx2 syntaxin 2

Primary Identifier  MGI:108059 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  13852
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables calcium-dependent protein binding activity. Involved in acrosome reaction. Acts upstream of or within cell differentiation. Located in several cellular components, including cell surface; cell-cell junction; and membrane raft. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; nervous system; and respiratory system. Orthologous to human STX2 (syntaxin 2).
PHENOTYPE: Mice homozygous for a null allele display male infertility associated with abnormal testicular development and impaired spermatogenesis, increased intestinal growth due to enhanced crypt cell proliferation and crypt fission, and decreased susceptibility to induced colitis. [provided by MGI curators]
  • synonyms:
  • AW538950,
  • reproductive mutation 34, JAX Reproductive Mutagenesis Program,
  • MGI:3692873,
  • Epim,
  • MGD-MRK-37095,
  • repro34,
  • Syn-2,
  • expressed sequence AW538950,
  • G1-536-1,
  • Stx2,
  • epimorphin,
  • MGI:2141213,
  • syntaxin 2

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For