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Allele : Gata4<em1Vigr> GATA binding protein 4; endonuclease-mediated mutation 1, Robert S Viger
Primary Identifier  MGI:7280955 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Gata4
Strain of Origin  (C57BL/6J x C3H/HeJ)F1/J Is Recombinase  false
Is Wild Type  false
molecularNote  Using an sgRNA and an ssODN template (gctcccaagggactatcctggcctagccctgctaaacacaaaacacttcctttctatgttgtagGcGgcttcccgccgggtaggcctctcctgtgccaactgccagactaccaccaccacg) with CRISPR/Cas9 technology, serine codon 261 (TCC) was changed to alanine (GCG) (p.S261A). This mutation blocks the phosphorylation of the residue.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • GATA4 S261A,
  • GATA4 S261A
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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3 Publication categories

Trail: Allele




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