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Protein Coding Gene : Slc39a2 solute carrier family 39 (zinc transporter), member 2

Primary Identifier  MGI:2684326 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  214922
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables zinc ion transmembrane transporter activity. Involved in keratinocyte differentiation and zinc ion transmembrane transport. Acts upstream of or within zinc ion transport. Located in plasma membrane. Is expressed in several structures, including genitourinary system; gut; liver; spleen; and yolk sac. Orthologous to human SLC39A2 (solute carrier family 39 member 2).
PHENOTYPE: Homozygotes for a null allele are overtly normal when fed a zinc-replete diet but show increased sensitivity to the effects of maternal dietary zinc deficiency during pregnancy. Resulting embryos are often growth retarded with craniofacial and limb defects, and show altered iron and calcium levels. [provided by MGI curators]
  • synonyms:
  • Gm1789,
  • MGI:2685135,
  • zip2,
  • RIKEN cDNA F730005G13 gene,
  • MGI:2686635,
  • gene model 1789, (NCBI),
  • F730005G13Rik,
  • Gm289,
  • solute carrier family 39 (zinc transporter), member 2,
  • gene model 289, (NCBI),
  • Slc39a2

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For