| Primary Identifier | MGI:2142008 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 101631 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable NuRD complex binding activity. Involved in chromatin remodeling; positive regulation of transcription elongation by RNA polymerase II; and regulation of cold-induced thermogenesis. Located in nucleus. Orthologous to human PWWP2B (PWWP domain containing 2B). PHENOTYPE: Mice homozygous for a conditional allele activated in adipose tissue exhibit increased adaptive thermogenesis and protection from high-fat diet induced obesity and metabolic dysregulation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
