Primary Identifier | MGI:3510038 | Allele Type | Targeted |
Attribute String | Conditional ready, Hypomorph | Gene | Tbx1 |
Transmission | Germline | Strain of Origin | 129/Sv |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This is a hypomorphic allele created by the insertion of an FRT-flanked neomycin resistance gene into intron 3, and loxP sites flanking exons 4-8, which encode the T-box region. RT-PCR from mutant embryos revealed that transcript levels were only 25% of the levels of wild-type. |