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Allele : Med1<tm1Rgr> mediator complex subunit 1; targeted mutation 1, Robert G Roeder

Primary Identifier  MGI:1861125 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Med1
Inheritance Mode  Recessive Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  A lacZ-PGK-neo cassette was inserted via homologous recombination resulting in deletion of most of the gene product, including loss of all LXXLL motifs and nuclear receptor coactivator function. Reporter gene assays showed expression was greatly reduced in mouse embyonic fibroblasts cultured from homozygous mutant embyros.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Trap220<->,
  • Trap220<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

10 Publication categories

Trail: Allele