| Primary Identifier | MGI:97852 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 109905 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables GTPase activity and small GTPase binding activity. Involved in positive regulation of vasculogenesis. Acts upstream of or within several processes, including negative regulation of synaptic vesicle exocytosis; positive regulation of ERK1 and ERK2 cascade; and small GTPase-mediated signal transduction. Located in several cellular components, including cell junction; neuron projection; and sperm midpiece. Part of guanyl-nucleotide exchange factor complex. Is expressed in brain; early conceptus; eye; hemolymphoid system gland; and oocyte. Orthologous to human RAP1A (RAP1A, member of RAS oncogene family). PHENOTYPE: Mice homozygous for a null allele exhibit impaired leukocyte migration and decreased angiogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
