First Author | Ziegler SF | Year | 1996 |
Journal | Genomics | Volume | 37 |
Issue | 1 | Pages | 19-23 |
PubMed ID | 8921365 | Mgi Jnum | J:35797 |
Mgi Id | MGI:83242 | Doi | 10.1006/geno.1996.0515 |
Citation | Ziegler SF, et al. (1996) Molecular characterization of a nonneuronal human UNC18 homolog. Genomics 37(1):19-23 |
abstractText | A cDNA clone encoding a human homolog of the Caenorhabditis elegans unc-18 gene was identified following random sequencing of clones from IL-2-activated human NK cells. This cDNA clone is related to the nonneuronal Munc-18b and so has been called Hunc-18b. The Hunc-18b transcripts were found in most human tissues, with the exception of brain and skeletal muscle, and in cells from all lymphoid lineages. The Hunc-18b gene was localized to human chromosome 19p13.2-p13.3, and the mouse homolog, Munc-18b, was mapped to the proximal region of mouse Chromosome 8. |