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Protein Coding Gene : Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase

Primary Identifier  MGI:1916363 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  69113
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables broad specificity oxidative DNA demethylase activity; cytosine C-5 DNA demethylase activity; and oxidative RNA demethylase activity. Predicted to be involved in DNA dealkylation; cell population proliferation; and oxidative single-stranded RNA demethylation. Predicted to act upstream of or within DNA damage response. Predicted to be located in cytosol; mitochondrion; and nucleoplasm. Predicted to be active in nucleus. Orthologous to human ALKBH3 (alkB homolog 3, alpha-ketoglutarate dependent dioxygenase).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit a normal lifespan and are phenotypically indistinguishable from control littermates. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 1700108H04 gene,
  • 1810020C19Rik,
  • Alkbh3,
  • MGI:1920823,
  • alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase,
  • RIKEN cDNA 1810020C19 gene,
  • Abh3,
  • mABH3,
  • 1700108H04Rik

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