Primary Identifier | MGI:1916363 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 69113 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables broad specificity oxidative DNA demethylase activity; cytosine C-5 DNA demethylase activity; and oxidative RNA demethylase activity. Predicted to be involved in DNA dealkylation; cell population proliferation; and oxidative single-stranded RNA demethylation. Predicted to act upstream of or within DNA damage response. Predicted to be located in cytosol; mitochondrion; and nucleoplasm. Predicted to be active in nucleus. Orthologous to human ALKBH3 (alkB homolog 3, alpha-ketoglutarate dependent dioxygenase). PHENOTYPE: Mice homozygous for a knock-out allele exhibit a normal lifespan and are phenotypically indistinguishable from control littermates. [provided by MGI curators] |