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Protein Domain : Alpha-ketoglutarate-dependent dioxygenase alkB homologue 6

Primary Identifier  IPR032862 Type  Family
Short Name  ALKBH6
description  Based on homology with E. coli AlkB, nine mammalian AlkB homologues have been identified. Like E. coli AlkB, ALKBH2 and ALKBH3 have been shown to possess DNA repair activity. However, findings suggest a wide functional diversity for other mammalian AlkB proteins, with substrates ranging from DNA and RNA to protein [, ].AlkB homologue 6 (ALKBH6) is a probable dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron. Its function is not known.

0 Child Features

0 Parent Features

3 Protein Domain Regions