First Author | Szpirer C | Year | 1995 |
Journal | Cytogenet Cell Genet | Volume | 69 |
Issue | 1-2 | Pages | 11-4 |
PubMed ID | 7835077 | Mgi Jnum | J:23298 |
Mgi Id | MGI:71061 | Doi | 10.1159/000133927 |
Citation | Szpirer C, et al. (1995) Chromosomal localization of the human and rat genes (PDE4D and PDE4B) encoding the cAMP-specific phosphodiesterases 3 and 4. Cytogenet Cell Genet 69(1-2):11-4 |
abstractText | Through the use of somatic cell hybrids segregating either human or rat chromosomes, we determined the chromosome localizations of two genes encoding cAMP-specific phosphodiesterases (cAMP-PDEs). PDE4D, the gene encoding the cAMP-PDE isoform 3 (IVd), was assigned to human chromosome 5 and rat chromosome 2, and PDE4B, the gene encoding the cAMP-PDE isoform 4 (IVb), was assigned to human chromosome 1 and rat chromosome 5. These localizations extend the homology between rat chromosome 2 and human chromosome 5, on the one hand, and between rat chromosome 5 and human chromosome 1, on the other hand. |