| Primary Identifier | MGI:2446084 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 216795 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within several processes, including embryonic morphogenesis; negative regulation of chondrocyte differentiation; and positive regulation of smoothened signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain; craniocervical region bone; limb; reproductive system; and urethra. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human WNT9A (Wnt family member 9A). PHENOTYPE: Homozygous inactivation of this gene results in neonatal lethality, altered chondrocyte maturation, cranial defects, and skeletal abnormalities including shortened appendicular long bones, partial joint fusions of carpal and tarsal elements, and chondroid metaplasia in synovial and fibrous joints. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
