| Primary Identifier | MGI:5703730 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Prnp-MAPT*R406W)21807Dwst |
| Strain of Origin | FVB/N | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The Syrian hamster prion protein promoter drives the expression of the longest form of the human four-repeat tau with the R406W mutation. Lines 21807, 21783, and 21768 were established. RT-PCR confirmed expression of mRNA in the brain and Western blot analysis shows that expression level is about 80% that of the endogenous mouse levels. |
