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Protein Coding Gene : Ttll6 tubulin tyrosine ligase-like family, member 6
Primary Identifier  MGI:2683461 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  237930
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables tubulin binding activity and tubulin-glutamic acid ligase activity. Involved in regulation of cilium beat frequency involved in ciliary motility. Acts upstream of or within microtubule bundle formation; microtubule severing; and positive regulation of cilium movement. Located in 9+0 non-motile cilium and ciliary basal body. Is expressed in several structures, including branchial arch; early embryo; genitourinary system; inner ear; and primitive streak. Orthologous to human TTLL6 (tubulin tyrosine ligase like 6).
  • synonyms:
  • 4932418K24Rik,
  • DNA segment, Chr 11, KL Mohlke 43 expressed,
  • D11Moh43e,
  • MGI:1343167,
  • t8130b59,
  • D11Moh44e,
  • tubulin tyrosine ligase-like family, member 6,
  • DNA segment, Chr 11, KL Mohlke 44 expressed,
  • Ttll6,
  • MGI:1343181,
  • RIKEN cDNA 4932418K24 gene
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Features --> Cross References

Genome

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2 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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