Primary Identifier | MGI:3850117 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Efnb1 |
Transmission | Germline | Strain of Origin | 129S4/SvJaeSor |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 4. An additional loxP site was inserted downstream of exon 5 followed by a modified exon 5 in which the last valine residue is deleted. Cre mediated recombination to remove the wild-type exon 5 is needed to allow for expression of the modified exon 5. |