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Protein Domain : Mature-T-Cell Proliferation I type

Primary Identifier  IPR027179 Type  Family
Short Name  MTCP1
description  Proteins in this family adopt a coiled coil structure, with two antiparallel α-helices that are tightly strapped together by two disulfide bridges at each end. The protein sequence shows a cysteine motif, required for the stabilisation of the coiled-coil-like structure. Additional inter-helix hydrophobic contacts impart stability to this scaffold [].The precise function of this family is, as yet, unknown []. MTCP1 is found in mitochondria. Mature-T-Cell Proliferation is the first gene unequivocally identified in the group of uncommon leukemias with a mature phenotype [].

0 Child Features

0 Parent Features

4 Protein Domain Regions