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Protein Coding Gene : Tmbim1 transmembrane BAX inhibitor motif containing 1
Primary Identifier  MGI:1916910 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  69660
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable death receptor binding activity. Involved in positive regulation of blood vessel remodeling. Predicted to be located in endosome membrane and lysosomal membrane. Predicted to be active in Golgi apparatus; endoplasmic reticulum; and membrane. Is expressed in esophagus epithelium; heart valve; naris; and stomach. Orthologous to human TMBIM1 (transmembrane BAX inhibitor motif containing 1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit susceptibility to cystic medial degeneration without inflammation or change in blood pressure and are prone to aortic dilation with age. [provided by MGI curators]
  • synonyms:
  • expressed sequence AU024746,
  • expressed sequence C78899,
  • Tmbim1,
  • RIKEN cDNA 2310061B02 gene,
  • 2310061B02Rik,
  • AU024746,
  • AA960455,
  • MGI:2146371,
  • MGI:2138482,
  • C78899,
  • expressed sequence AA960455,
  • transmembrane BAX inhibitor motif containing 1,
  • MGI:2138674
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Features --> Cross References

Genome

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2 Involved In Mutations

Trail: ProteinCodingGene

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0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

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Interactions

3 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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