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Publication : Amino acid-induced responses in CNS neurons of normal mouse and Wriggle Mouse Sagami.

First Author  Furukawa K Year  1994
Journal  Neuroreport Volume  5
Issue  12 Pages  1530-2
PubMed ID  7948855 Mgi Jnum  J:22154
Mgi Id  MGI:70036 Doi  10.1097/00001756-199407000-00030
Citation  Furukawa K, et al. (1994) Amino acid-induced responses in CNS neurons of normal mouse and Wriggle Mouse Sagami. Neuroreport 5(12):1530-2
abstractText  Amino acid-induced responses and their regional heterogeneities in the motor cortical and hippocampal (CA1) neurons of normal mouse and Wriggle Mouse Sagami (WMS) were studied by conventional patch-clamp techniques. There were no differences in the current densities and EC50s of glutamate-, gamma-amino butyric acid (GABA)-, and glycine-induced responses between the two groups of mice. In both types of mice, the GABA-induced current density of cortical neurones was higher and EC50 was lower than in hippocampal neurones, whereas the responses induced by glycine and glutamate did not show any differences.
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