First Author | Furukawa K | Year | 1994 |
Journal | Neuroreport | Volume | 5 |
Issue | 12 | Pages | 1530-2 |
PubMed ID | 7948855 | Mgi Jnum | J:22154 |
Mgi Id | MGI:70036 | Doi | 10.1097/00001756-199407000-00030 |
Citation | Furukawa K, et al. (1994) Amino acid-induced responses in CNS neurons of normal mouse and Wriggle Mouse Sagami. Neuroreport 5(12):1530-2 |
abstractText | Amino acid-induced responses and their regional heterogeneities in the motor cortical and hippocampal (CA1) neurons of normal mouse and Wriggle Mouse Sagami (WMS) were studied by conventional patch-clamp techniques. There were no differences in the current densities and EC50s of glutamate-, gamma-amino butyric acid (GABA)-, and glycine-induced responses between the two groups of mice. In both types of mice, the GABA-induced current density of cortical neurones was higher and EC50 was lower than in hippocampal neurones, whereas the responses induced by glycine and glutamate did not show any differences. |