Primary Identifier | MGI:3814340 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Igh |
Transmission | Germline | Strain of Origin | (C57BL/6J x 129S6/SvEvTac)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The entire JHwas replaced with a rearranged VDJ exon carrying a translational stop codon at amino acid position 3 of the leader peptide and a floxed neomycin resistance cassette. Mutant mice were crossed with Tg(EIIa-cre)C5379Lmgd mice resulting in excision of the selection cassette. |