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Allele : Nfkbie<tm1Syme> nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon; targeted mutation 1, Sylvie Memet

Primary Identifier  MGI:3034029 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Nfkbie
Transmission  Germline Strain of Origin  129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase  false Is Wild Type  false
molecularNote  The entire coding region was replaced with a lacZ gene and associated nuclear localization sequence followed by IRES and promoterless neomycin gene. Northern blot analysis established the absence of transcripts while Western blot analysis demonstrated that no protein product was present. Beta-galactosidase expression was detected in the medulla of the lymph node, and a few cells of the thymus and spleen.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • IkappaBepsilon<->,
  • IkappaBepsilon<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories

Trail: Allele