First Author | Williams AF | Year | 1982 |
Journal | Science | Volume | 216 |
Issue | 4547 | Pages | 696-703 |
PubMed ID | 6177036 | Mgi Jnum | J:32621 |
Mgi Id | MGI:80114 | Doi | 10.1126/science.6177036 |
Citation | Williams AF, et al. (1982) Neuronal cell Thy-1 glycoprotein: homology with immunoglobulin. Science 216(4547):696-703 |
abstractText | The amino acid sequences of mouse brain Thy-1 glycoproteins are shown to be homologous to those of variable-region immunoglobulin domains. There is also good homology with constant domains and beta 2-microglobulin; overall the results suggest that Thy-1 may be like the primordial immunoglobulin domain. Preliminary evidence for an invertebrate Thy-1 homolog supports this possibility. |