Primary Identifier | MGI:3603317 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Casp7 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The targeting construct replaces exons 2 and 3 with a neomycin resistance cassette, and also results in a frame-shift. Western blot analysis showed absence of caspase 7 expression in homozygous mice. |