First Author | Owen FL | Year | 1983 |
Journal | J Exp Med | Volume | 157 |
Issue | 2 | Pages | 419-32 |
PubMed ID | 6600486 | Mgi Jnum | J:6951 |
Mgi Id | MGI:55422 | Doi | 10.1084/jem.157.2.419 |
Citation | Owen FL (1983) Tpre, a new alloantigen encoded in the IgT-C region of chromosome 12, is expressed on bone marrow of nude mice, fetal T cell hybrids, and fetal thymus. J Exp Med 157(2):419-32 |
abstractText | A new T cell alloantigen, Tpre, has been identified by monoclonal F.6.9.1 antibody. This antigen is encoded by a gene linked to the cluster of T cell antigens in the IgT-C region of chromosome 12 (Tthy, Tind, and Tsu). Tpre is distinct from Tthy, Tind, or Tsu because it is expressed on bone marrow cells of the AKR nustr/nustr, the thymus repopulating precursor cell in normal adult marrow, and normal fetal thymocytes. Several fetal and adult T cell hybrids express these antigens independently. Tpre and Tthy are expressed on largely overlapping cell populations in adult thymus. |