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Protein Coding Gene : Med23 mediator complex subunit 23

Primary Identifier  MGI:1917458 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  70208
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to contribute to ubiquitin protein ligase activity. Acts upstream of or within positive regulation of T cell extravasation and positive regulation of gene expression. Part of mediator complex. Is expressed in several structures, including genitourinary system. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 18. Orthologous to human MED23 (mediator complex subunit 23).
PHENOTYPE: Homozygous null mice display embryonic lethality during organogenesis with disorganization of the vasculature and peripheral nervous system. [provided by MGI curators]
  • synonyms:
  • 3000002A17Rik,
  • sno,
  • ESTM7,
  • MGI:5004966,
  • mediator complex subunit 23,
  • Sur2,
  • RIKEN cDNA 3000002A17 gene,
  • X83317,
  • Med23,
  • EST X83317,
  • snouty,
  • mKIAA1216,
  • Crsp3,
  • cofactor required for Sp1 transcriptional activation, subunit 3,
  • expressed sequence tag mouse EST 7,
  • MGD-MRK-28117,
  • MGI:104823

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For