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Protein Domain : Mesoderm induction early response protein 1

Primary Identifier  IPR031169 Type  Family
Short Name  MIER1
description  MIER1 is a transcriptional regulator identified from a screen for fibroblast growth factor early response genes that are activated during mesoderm induction in Xenopus laevis embryos []. MIER1 has been shown to repress transcription using several distinct mechanisms [, ], including recruitment of histone deacetylase 1 (HDAC1) []. The protein consists of several isoforms with a common internal region and variable N- and C- termini []. The common region contains an ELM2 domain and a SANT domain, both of which play a role in transcriptional regulation [, ].

0 Child Features

1 Parent Features

3 Protein Domain Regions