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Allele : Del(7Coro1a-Spn)1Dolm deletion, Chr 7, Ricardo Dolmetsch 1
Primary Identifier  MGI:5569506 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Del(7Coro1a-Spn)1Dolm
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Two sequential targeting events generated Igs14tm1Dolm and Igs13tm1Dolm. Cre-mediated recombination removed both floxed neomycin cassettes creating a deletion that spans 440 kbp region on mouse chromosome 7F3 (between and including Coro1a to Spn); a region highly conserved with the human chromosome 16p11.2 region whose copy number variations are associated with autism spectrum disorders and schizophrenia.
  • mutations:
  • Intragenic deletion,
  • Intergenic deletion
  • synonyms:
  • 16p11<->,
  • 16p11<->,
  • 16p11.2,
  • 16p11.2
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1 Feature

Trail: Allele

Genome

0 Expresses

39 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele




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